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Name: Clonazolam (6-(2-chlorophenyl)-1-methyl-8-nitro-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine
Type: Benzodiazepine
AKA: N/A
![Clonazolam (6-(2-chlorophenyl)-1-methyl-8-nitro-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine image](https://grammasearch.com/dev/v2/aiimages/clonazolam_%286-%282-chlorophenyl%29-1-methyl-8-nitro-4h-benzo%5Bf%5D%5B1%2C2%2C4%5Dtriazolo%5B4%2C3-a%5D%5B1%2C4%5Ddiazepine.png)
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II. Natural Derivative
Synthetic substance, no natural derivative
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III. Chemical Profile (IUPAC name)
![Clonazolam (6-(2-chlorophenyl)-1-methyl-8-nitro-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine image](/dev/v2/pages/pubchem_images/44720012.png)
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IV. History
Clonazolam, a thienodiazepine, was first developed in the 1970s. It was introduced for its anxiolytic and hypnotic effects, similar to benzodiazepines. The compound gained popularity for its effectiveness in treating anxiety and sleep disorders. Clonazolam's use has been subject to regulatory controls due to its potential for abuse and dependence.
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V. Legal Information
Clonazolam is a benzodiazepine derivative with anxiolytic and sedative effects. It is controlled due to its potential for abuse and dependence, with increasing international regulation. [Source: UNODC].
US Federal Schedule - I
Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse. Some examples of Schedule I drugs are: heroin, lysergic acid diethylamide (LSD), marijuana (cannabis), 3,4-methylenedioxymethamphetamine (ecstasy), methaqualone, and peyote.
Key US Federal Policies:
Controlled Substances Act. Public Law: Public Law 91-513 (text can be found on GovInfo) (https://www.dea.gov/drug-information/csa). Date enacted: October 27, 1970.
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VI. Physical Effects
Clonazolam is a benzodiazepine with anxiolytic and sedative effects. It acts as a downer, causing sedation, muscle relaxation, and reduced heart rate. Short-term use can help with anxiety and sleep disorders, but long-term use may lead to dependence, cognitive impairment, and health issues. Overdose risks include severe sedation, respiratory depression, and potential death. Safe use involves following prescribed dosages and monitoring for side effects. Recent research explores its efficacy and safety profile.  |
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VII. Psychological Effects
Clonazolam is a benzodiazepine causing sedation, anxiolysis, and muscle relaxation. Immediate effects include reduced anxiety, improved mood, and sedation. Long-term use can result in dependence, tolerance, and withdrawal symptoms. Chronic use is associated with cognitive impairment, depressive disorders, and increased anxiety. Recent studies indicate benzodiazepines can lead to structural changes in the brain.
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VIII. Culture
Clonazolam is a benzodiazepine used for its anxiolytic and sedative effects, classifying it as a downer. Short-term use induces sedation and anxiety relief, while long-term use can lead to dependence, tolerance, and cognitive impairment. Overdose risks include severe sedation, respiratory depression, and potential coma. Safe dosages are prescribed by medical professionals. Recent research highlights its effectiveness in treating anxiety but warns of high dependence risks and cognitive effects. Physical effects include drowsiness, impaired coordination, and potential respiratory depression.
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